Jin Guangfu

发布者：十大体育外围平台网址发布时间：2022-10-23浏览次数：592


Guangfu Jin,PhD

Professor , Department  of  Epidemiology , Nanjing Medical University

Associate Dean,School  of  Public Health , Nanjing Medical University

Vice Director , Collaborative Innovation Center for Cancer Personalized Medicine

Associate  Editor , Cancer Medicine

Associate  Editor , Cancer Science

Email :guangfujin@njmu.edu.cn




Research Interest

Dr. Jin mainly engaged inmolecular epidemiology and genetic epidemiology, especially focusing on cancer biomarkers and personalized medicine, including: 

1) Identifying high-risk population of cancer by integrating traditional factors and new biomarkers, and developing technologies, tools and strategies for cancer prevention and control; 

2) Discovering  molecular biomarkers for molecular diagnosis, individualized treatment, dynamic monitoring, and prognosis prediction to promote accurate diagnosis and treatment of cancer; 

3) Clarifying biological functions and molecular mechanisms of related biomarkers in the process of multi-stage carcinogenesis.

 

Education

Nanjing  Medical  University, Preventive Medicine, B.S. (1999.9-2004.7)

Nanjing  Medical  University, Epidemiology and Biostatistics, Ph.D.(2004.9-2009.7)

Wake  Forest  University, School of  Medicine, Postdoctoral Fellow (2010.8-2012.2)


Honors and Awards:

2018   National Natural Science Award of  China (Second Class)

2020  Award for Young Cancer Scientist of  China


Ongoing Research Projects

  • PI,  Biological mechanisms of germline variants and somatic mutations in  the  development  of  gastric  cancer.NSFC,81872702

  • PI,  Molecular and genetic epidemiology. NSFC, 82125033


Selected Papers

  1. Zhu M, Wang T,Huang Y, Zhao X, Ding Y, Zhu M, Ji M, Wang C, Dai J, Yin R, Xu L, MaH, Wei Q, Jin G,Hu Z, Shen H. Genetic Risk for Overall Cancer and the Benefit of Adherence to a Healthy Lifestyle. CancerRes.2021 Sep;81(17):4618-4627.

  2. Jin G,Lv J, Yang M, Wang M, Zhu M, Wang T, Yan C, Yu C, Ding Y, Li G, RenC, Ni J, Zhang R, Guo Y, Bian Z, Zheng Y, Zhang N, Jiang Y, Chen J,Wang Y, Xu D, Zheng H, Yang L, Chen Y, Walters R, Millwood IY, DaiJ, Ma H, Chen K, Chen Z, Hu Z, Wei Q, Shen H, Li L. Genetic risk, incident gastric cancer, and healthy lifestyle: a meta-analysis of genome-wide association studies and prospective cohort study. LancetOncol.2020 Oct; 21(10):1378-1386.

  3. Yan C, Zhu M, DingY, Yang M, Wang M, Li G, Ren C, Huang T, Yang W, He B, Wang M, Yu F,Wang J, Zhang R, Wang T, Ni J, Chen J, Jiang Y, Dai J Zhang E, Ma H,Wang Y, Xu D, Wang S, Chen Y, Xu Z, Zhou J, Ji G, Wang Z, Zhang Z,Hu Z, Wei Q, Shen H, Jin G. Meta-analysis of genome-wide association studies and functional assays decipher susceptibility genes for gastric cancer in Chinese populations. Gut.2020;69(4):641-651.

  4. Yu F, Tian T, DengB, Wang T, Qi Q, Zhu M, Yan C, Ding H, Wang J, Dai J, Ma H, Ding Y,Jin G.Multi-marker analysis of genomic annotation on gastric cancer GWAS data from Chinese populations.GastricCancer.2019; 22(1):60-68.

  5. Yan C, Zhu M, HuangT, Yu F, Jin G.Genome-wide association studies identified loci contribute to phenotypic variance of gastric cancer.Gut.2018;67(7):1366-1368.

  6. Yan C, Ji Y, HuangT, Yu F, Gao Y, Gu Y, Qi Q, Du J, Dai J, Ma H, Jin G.An esophageal adenocarcinoma susceptibility locus at 9q22 alsoconfers risk to esophageal squamous cell carcinoma by regulating the function of BARX1. CancerLett.2018 May 1;421:103-111.

  7. Zhu M, Yan C, RenC, Huang X, Zhu X, Gu H, Wang M, Wang S, Gao Y, Ji Y, Miao X, YangM, Chen J, Du J, Huang T, Jiang Y, Dai J, Ma H, Zhou J, Wang Z, HuZ, Ji G, Zhang Z, Shen H, Shi Y, Jin G.Exome Array Analysis Identifies Variants in SPOCD1 and BTN3A2 That  Affect  Risk for  Gastric Cancer. Gastroenterology.2017;152(8):2011-2021.

  8. Jin G,Zhu M, Yin R, Shen W, Liu J, Sun J, Wang C, Dai J, Ma H, Wu C, etal. Low-frequency coding variants at 6p21.33 and 20q11.21 are associated with lung cancer risk in Chinese populations. AmJ Hum Genet.2015;96(5):832-40.

  9. Zhu C, Ren C, HanJ, Ding Y, Du J, Dai N, Dai J, Ma H, Hu Z, Shen H, Xu Y*, JinG*.A five-microRNA panel in plasma was identified as potential biomarker for early detection of gastric cancer. BrJ Cancer.2014;110(9):2291-9.

  10. Jin G,Ma H, Wu C, Dai J, Zhang R, Shi Y, Lu J, Miao X, Wang M, Zhou Y, etal. Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers: evidence from three genome-wide association studies on different cancers in Han Chinese populations. AmJ Hum Genet.2012;91(5):928-34.

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